April 7th, 2008
Biotransformation in vitro of the 22R and 22S epimers of budesonide by human liver, bronchus, colonic mucosa and skin
Budesonide is a synthetic glucocorticosteroid used in the topical treatment of diseases such as rhinitis, asthma and psoriasis , which has also been introduced for the treatment of inflammatory bowel disease. This drug is characterized by a high local potency at the site of application with relatively low systemic activity after absorption. This high therapeutic [...]
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